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Is Meprobamate a Benzodiazepine? - Addict Advice

Is Meprobamate a Benzodiazepine?

Meprobamate has been used for years as a medication for treating anxiety and insomnia, but is it a benzodiazepine? Benzodiazepines, commonly known as “benzos”, are a type of sedative-hypnotic drug used to treat anxiety, panic attacks, and insomnia. As such, it is important to know if meprobamate is a benzodiazepine in order to understand its effects and potential risks. In this article, we will discuss the similarities and differences between meprobamate and benzodiazepines in order to answer the question: is meprobamate a benzodiazepine?

Is Meprobamate a Benzodiazepine?

What is Meprobamate and Is It a Benzodiazepine?

Meprobamate is a centrally acting muscle relaxant that was first marketed in the 1950s. It is a pro-drug of carisoprodol, and it is a metabolite of meprobamate. It is sometimes referred to as a sedative-hypnotic, but it does not have the same effects as benzodiazepines. Meprobamate is not a benzodiazepine, but it does have some similar effects. It is commonly used to treat anxiety and tension, as well as insomnia.

Meprobamate is a carboxamide derivative of meprobamate, an anticonvulsant and sedative-hypnotic drug. It has similar effects to benzodiazepines, such as reducing anxiety and tension, but it does not act on the same receptors as benzodiazepines. Meprobamate can also be used to treat insomnia, but it is not as effective as benzodiazepines.

Meprobamate is an intermediate-acting drug, which means that its effects last for a shorter period of time compared to benzodiazepines. It is also less potent than benzodiazepines, so it is generally not as effective at treating anxiety or insomnia. Additionally, meprobamate is not as safe as benzodiazepines, as it has the potential to cause physical dependence, particularly with long-term use.

How Does Meprobamate Work?

Meprobamate works by inhibiting the action of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that is responsible for calming the nervous system and reducing anxiety. By blocking the action of GABA, meprobamate increases the activity of other neurotransmitters, such as glutamate and acetylcholine, which can then reduce anxiety and tension.

Meprobamate also acts on the hypothalamus and limbic system, which are responsible for regulating mood and emotion. It has been shown to reduce anxiety and tension, as well as improve mood. Meprobamate can also increase the amount of time spent in deep sleep, which can improve sleep quality and reduce insomnia.

What Are the Side Effects of Meprobamate?

Meprobamate is a safe drug when taken as prescribed, but it can cause some side effects. The most common side effects include drowsiness, dizziness, headache, nausea, and vomiting. Other side effects may include confusion, depression, irritability, blurred vision, and an increase in appetite.

Long-term use of meprobamate can cause physical dependence and withdrawal symptoms. Common withdrawal symptoms include anxiety, insomnia, nausea, and muscle pain. It is important to stop taking meprobamate gradually to avoid the risk of severe withdrawal symptoms.

What Are the Interactions of Meprobamate?

Meprobamate may interact with other medications, such as sedatives, hypnotics, and alcohol. These interactions may lead to an increased risk of drowsiness, confusion, and impaired thinking. It is important to speak with a doctor to determine if any medications or alcohol should be avoided while taking meprobamate.

Meprobamate may also interact with certain supplements, such as ginkgo biloba and St. John’s wort. These interactions can increase the risk of side effects, so it is important to speak with a doctor before taking any supplements.


Meprobamate is a centrally acting muscle relaxant that is sometimes referred to as a sedative-hypnotic, but it is not a benzodiazepine. It has similar effects to benzodiazepines, such as reducing anxiety and tension, but it is not as potent or as safe. Meprobamate can cause side effects, such as drowsiness, dizziness, headache, and nausea, and long-term use can cause physical dependence. It is important to speak with a doctor before taking meprobamate to ensure that it is safe and to avoid any interactions.

Related Faq

Q1. Is Meprobamate a Benzodiazepine?

A1. No, Meprobamate is not a benzodiazepine. It is a carbamate antianxiety drug that was developed in the 1950s and was once very popular in the U.S. for the treatment of anxiety. While Meprobamate is chemically similar to benzodiazepines, it does not have the same pharmacological effects as benzodiazepines and does not have the same potential for abuse or addiction.

Q2. How does Meprobamate work?

A2. Meprobamate works by increasing levels of the inhibitory neurotransmitter GABA in the brain. GABA is a chemical messenger that helps to reduce the activity of neurons in the brain, leading to a calming effect. Meprobamate can also inhibit the release of other neurotransmitters, such as glutamate and serotonin, which can also help reduce anxiety levels.

Q3. What are the side effects of Meprobamate?

A3. Common side effects of Meprobamate can include drowsiness, dizziness, headache, blurred vision, dry mouth, tremor, and nausea. More serious side effects can include confusion, difficulty breathing, and an irregular heartbeat. It is important to contact a doctor if any of these side effects occur.

Q4. What is the dosage for Meprobamate?

A4. The dosage for Meprobamate will vary depending on individual needs and other factors. The usual starting dose is 400 mg taken three times a day, with the maximum dose being 1200 mg per day. It is important to follow the instructions of a doctor when taking Meprobamate, as it can be dangerous to take too much of the medication.

Q5. Are there any interactions between Meprobamate and other drugs?

A5. Yes, Meprobamate can interact with certain other drugs. It is important to tell a doctor or pharmacist about any other medications that are being taken, as well as any vitamins, herbal supplements, and over-the-counter medications. Combining Meprobamate with alcohol can also increase the risk of serious side effects.

Q6. Is Meprobamate safe for long-term use?

A6. Meprobamate is not generally recommended for long-term use due to the risk of dependence and tolerance. It is important to take it only as prescribed and to discuss any concerns with a doctor. If taken for long periods of time, it can be dangerous to suddenly stop taking Meprobamate, as this can cause withdrawal symptoms.

Meprobamate and Benzodiazepine Meprobamate

Meprobamate is an effective medication for many people, but it is not a benzodiazepine. Meprobamate works as a muscle relaxant and anticonvulsant, and has been used to treat anxiety and insomnia since the 1950s. While it has similar effects to benzodiazepines, the two drugs are very different in terms of their chemical structure and how they interact with the body. Meprobamate should be used with caution and never substituted for a benzodiazepine.

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